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Amnesty International is one of the notable groups calling for the decriminalization of prostitution. Others view sex work as a legitimate occupation, whereby a person trades or exchanges sexual acts for money. This approach has also been adopted by Canada, Iceland, Ireland, Northern Ireland, Norway, France and Sweden. Some critics of prostitution as an institution are supporters of the ' Nordic model' that decriminalizes the act of selling sex and makes the purchase of sex illegal. Some view prostitution as a form of exploitation of or violence against women, and children, that helps to create a supply of victims for human trafficking. The position of prostitution and the law varies widely worldwide, reflecting differing opinions. The majority of prostitutes are female and have male clients. Estimates place the annual revenue generated by prostitution worldwide to be over $100 billion. There are about 42 million prostitutes in the world, living all over the world (though most of Central Asia, the Middle East and Africa lack data, studied countries in that large region rank as top sex tourism destinations). In escort prostitution, the act may take place at the client's residence or hotel room (referred to as out-call), or at the escort's residence or a hotel room rented for the occasion by the escort (in-call). Brothels are establishments specifically dedicated to prostitution. It is one branch of the sex industry, along with pornography, stripping, and erotic dancing. Prostitution occurs in a variety of forms, and its legal status varies from country to country (sometimes from region to region within a given country), ranging from being an enforced or unenforced crime, to unregulated, to a regulated profession. A person who works in this field is called a prostitute, or more inclusively, a sex worker. It is sometimes referred to euphemistically as 'the world's oldest profession' in the English-speaking world.

Prostitution is sometimes described as sexual services, commercial sex or, colloquially, hooking. The requirement of physical contact also creates the risk of transferring diseases. The definition of 'sexual activity' varies, and is often defined as an activity requiring physical contact (e.g., sexual intercourse, non-penetrative sex, oral sex, etc.) with the customer. Prostitution is the business or practice of engaging in sexual activity in exchange for payment.

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